SERPINA1 Proteine
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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36 Treffer :
SERPINA1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SERPINA1
Spezies: Maus
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
SERPINA1
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
SERPINA1
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
SERPINA1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aktuelle Publikationen für unsere SERPINA1 Proteine
: "Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 11, pp. 2477-2489, (2017) (PubMed).: "Erratum to: Rectocutaneous fistula with transmigration of the suture: a rare delayed complication of vault fixation with the sacrospinous ligament." in: International urogynecology journal, Vol. 27, Issue 3, pp. 505, (2016) (PubMed).
: "LaCyTools: A Targeted Liquid Chromatography-Mass Spectrometry Data Processing Package for Relative Quantitation of Glycopeptides." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2198-210, (2016) (PubMed).
: "Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase." in: American journal of respiratory cell and molecular biology, Vol. 54, Issue 3, pp. 341-9, (2016) (PubMed).
: "Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification." in: Circulation research, Vol. 117, Issue 9, pp. 758-69, (2015) (PubMed).
: "The BLT1 Inhibitory Function of ?-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 8, pp. 3628-41, (2015) (PubMed).
: "Enhanced recognition of plasma proteins in a non-native state by complement C3b. A possible clearance mechanism for damaged proteins in blood." in: Molecular immunology, Vol. 64, Issue 1, pp. 55-62, (2015) (PubMed).
: "Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L80-7, (2014) (PubMed).
: "Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 3, pp. 1220-30, (2014) (PubMed).
Aliase für SERPINA1 Proteine
serpin family A member 3 (SERPINA3) Proteinealpha-1-antiproteinase F precursor (LOC100008973) Proteine
serpin family A member 1 (SERPINA1) Proteine
alpha-1-antitrypsin (LOC100328621) Proteine
calumenin (CALU) Proteine
serpin family A member 1 (Serpina1) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog (serpina1.S) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) Proteine
SH2B adaptor protein 2 (Sh2b2) Proteine
calumenin (Calu) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) Proteine
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog (serpina1.L) Proteine
A1A Proteine
A1AT Proteine
AACT Proteine
AAT Proteine
ACT Proteine
alpha-1-PI Proteine
alpha1AT Proteine
Aps Proteine
GIG25 Proteine
MGC64429 Proteine
PI Proteine
Pi Proteine
PI1 Proteine
PRO2275 Proteine
serpina1d Proteine
SERPINA3-5 Proteine
Spi1 Proteine
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