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SENP6 Proteine

(SUMO1/sentrin Specific Protease 6 (SENP6))
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA\; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009].

4 Treffer :

custom-made SENP6 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7564092
 
custom-made SENP6 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7555489
 
custom-made SENP6 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB
Produktnummer ABIN3135755
 
custom-made SENP6 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB
Produktnummer ABIN3095426
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
  • Bindungsspezifität
    • AA 1-1112
    • AA 1-1132
  • Konjugat
    • His tag
    • Strep Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online

Aliase für SENP6 Proteine

SUMO1/sentrin specific peptidase 6 (SENP6) Proteine
SUMO/sentrin specific peptidase 6 (Senp6) Proteine
SUMO1/sentrin specific peptidase 6 (Senp6) Proteine
SUMO1/sentrin specific peptidase 6a (senp6a) Proteine
2810017C20Rik Proteine
E130319N12Rik Proteine
fc83h02 Proteine
im:7148342 Proteine
mKIAA0797 Proteine
SSP1 Proteine
SUSP1 Proteine
Susp1 Proteine
wu:fc83h02 Proteine
zgc:171230 Proteine
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