SARS-CoV-2 Spike S1 Proteine
(SARS-CoV-2 Spike S1)
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: Tobacco (Nicotiana benthamiana)
Recombinant
≥ 85 %
Spezies: SARS Coronavirus (SARS-CoV)
Wirt: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
Active
Spezies: SARS Coronavirus (SARS-CoV)
Wirt: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
> 85 % by SDS-PAGE.
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: CHO Cells
Recombinant
>95 % as determined by SDS-PAGE and HPLC
Spezies: SARS Coronavirus-2 (SARS-CoV-2)
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
Aktuelle Publikationen für unsere SARS-CoV-2 Spike S1 Proteine
: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).: "Point-of-care (POC) SARS-CoV-2 antigen detection using functionalized aerosol jet-printed organic electrochemical transistors (OECTs)." in: Nanoscale, Vol. 15, Issue 11, pp. 5476-5485, (2023) (PubMed).
: "Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection." in: Stroke, Vol. 52, Issue 1, pp. 260-270, (2021) (PubMed).
: "Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 5, (2021) (PubMed).
: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
: "Protein Footprinting, Conformational Dynamics, and Core Interface-Adjacent Neutralization "Hotspots" in the SARS-CoV-2 Spike Protein Receptor Binding Domain/Human ACE2 Interaction." in: Journal of the American Society for Mass Spectrometry, (2021) (PubMed).
: "Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum." in: ACS infectious diseases, (2021) (PubMed).
: "Delayed production of neutralizing antibodies correlates with fatal COVID-19. ..." in: Nature medicine, (2021) (PubMed).
: "Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. ..." in: Cell reports. Medicine, pp. 100288, (2021) (PubMed).
: "A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. ..." in: Nature communications, Vol. 12, Issue 1, pp. 2623, (2021) (PubMed).
Aliase für SARS-CoV-2 Spike S1 Proteine
Surface Glycoprotein (S) ProteineE2 Proteine
Haben Sie etwas anderes gesucht?
- SARS-CoV-2 Spike Proteine
- SARS-CoV-2 Nucleocapsid Proteine
- SARS-CoV-2 NSP7 Proteine
- SARS-CoV-2 NSP5 (3CL-Pro) Proteine
- SARS-CoV-2 NSP3 Proteine
- SARS-CoV Spike Proteine
- SARS-Coronavirus Nucleocapsid Protein Proteine
- SARS-Coronavirus Membrane Protein Proteine
- SARNP Proteine
- SARM1 Proteine
- SARDH Proteine
- Sarcolemma Associated Protein Proteine
- Sarcalumenin Proteine
- SAR1B Proteine
- SAR1A Proteine
- SAPS2 Proteine
- SAPS1 Proteine
- SAP30BP Proteine
- SAP30-Like Proteine
- SAP30 Proteine
- SARS-CoV-2 Spike S2 Proteine
- SARS2 Proteine
- SART1 Proteine
- SART3 Proteine
- SASH1 Proteine
- SASH3 Proteine
- SAT1 Proteine
- SAT2 Proteine
- SATB1 Proteine
- SATB2 Proteine
- SAV1 Proteine
- SBDS Proteine
- SBEM Proteine
- SBK1 Proteine
- SBNO1 Proteine
- SC4MOL Proteine
- SC5DL Proteine
- SCAMP1 Proteine
- SCAMP3 Proteine
- SCAND1 Proteine
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