The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009].
custom-made
SAT1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SAT1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SAT1
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Produktnummer ABIN3134175
ab
15.754,29 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
custom-made
SAT1
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Produktnummer ABIN3076674
ab
15.754,29 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
Sun, Liu, Yang, Xu, Yan, Wang, Liu: "Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro." in: Acta pharmacologica Sinica, Vol. 29, Issue 5, pp. 606-13, (2008) (PubMed).
Xiao, Celano, Mank, Griffin, Jabs, Hawkins, Casero: "Structure of the human spermidine/spermine N1-acetyltransferase gene (exon/intron gene organization and localization to Xp22.1)." in: Biochemical and biophysical research communications, Vol. 187, Issue 3, pp. 1493-502, (1992) (PubMed).
Casero, Celano, Ervin, Applegren, Wiest, Pegg: "Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase." in: The Journal of biological chemistry, Vol. 266, Issue 2, pp. 810-4, (1991) (PubMed).
Xiao, Celano, Mank, Pegg, Casero: "Characterization of a full-length cDNA which codes for the human spermidine/spermine N1-acetyltransferase." in: Biochemical and biophysical research communications, Vol. 179, Issue 1, pp. 407-15, (1991) (PubMed).