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SARS-CoV-2 Spike Proteine

(SARS-CoV-2 Spike)
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

151 Treffer :

Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA
Pubmed 2 Referenzen
Produktnummer ABIN6953302
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274399
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274398
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274388
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274385
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274387
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7490638
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7490659
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, WB
Produktnummer ABIN6961147
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA
Produktnummer ABIN6953299
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274871
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273901
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274402
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274395
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273903
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7273900
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275136
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274458
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274758
 
Spezies: SARS Coronavirus-2 (SARS-CoV-2) Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274490
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Control (Ct)
    • Enzyme Immunoassay (EIA)
    • Functional Studies (Func)
    • Lateral Flow (LF)
  • Reaktivität
    • SARS Coronavirus-2 (SARS-CoV-2)
    • SARS CoV-2 Omicron
    • SARS CoV-2 Delta
    • SARS CoV-2 Beta
    • SARS CoV-2 Alpha
    • SARS CoV-2 Gamma
    • SARS CoV-2 Kappa
    • SARS CoV-2 Delta plus
    • SARS-CoV-2 Lambda
    • SARS CoV-2 Epsilon
    • SARS CoV-2 XD
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Preservative free only
  • Wirt
    • HEK-293 Cells
    • Mammalian Cells
    • CHO Cells
    • Escherichia coli (E. coli)
    • Tobacco (Nicotiana benthamiana)
    • Human Cells
    • Insect Cells
  • Bindungsspezifität
    • RBD
    • Trimer
    • B.1.617.2 - delta
    • B.1.1.529 - Omicron
    • N501Y
    • B.1.351 - beta
    • BA.2 - Omicron
    • BA.4 - Omicron
    • BA.5 - Omicron
    • P.1 - gamma
    • Super Stable Trimer
    • XBB.1.5 - Omicron
    • B.1.1.7 - alpha
    • B.1.617.1 - kappa
    • B.1.617.2 - delta plus
    • BF.7 - Omicron
    • BQ.1.1 - Omicron
    • C.37 - Lambda
    • E484K
    • D614G
    • Leu452Arg
    • XBB - Omicron
    • BA.1 - Omicron
    • BA.2.12.1 - Omicron
    • BA.2.75 - Omicron
    • BA.2.76 - Omicron
    • ECD
    • K417N
    • N-Term
    • NTD
    • Thr478Lys
    • XBB.1 - Omicron
    • full length
    • AA 16-1213
    • AA 310-560
    • AA 331-524
    • Asn501Tyr
    • B.1.1.7 – alpha
    • B.1.351 – beta
    • B.1.429 - epsilon
    • B.1.617.2 – delta
    • B.1.640
    • BA.1 – Omicron
    • BA.2 – Omicron
    • BA.2.11 - Omicron
    • BA.2.38 - Omicron
    • BA.2.74 - Omicron
    • BA.2.75.2 - Omicron
    • BA.3 - Omicron
    • BQ.1 – Omicron
    Please use search to find more...
  • Konjugat
    • His tag
    • Biotin,His-Avi Tag
    • His tag,AVI tag,Biotin
    • Fc Tag
    • His-Avi Tag,Biotin
    • Unkonjugiert
    • His tag,Strep Tag
    • His-Avi Tag
    • mFc Tag
    • mFc Tag,AVI tag,Biotin
    • FITC,His tag
    • Fc-Avi Tag
    • Fc-Avi Tag,Biotin
    • HRP,His tag
    • His tag,AVI tag
    • His tag,HRP
    • mFc-His Tag
    • rFc Tag
    • sFc-Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • MALS verified
  • Hersteller
    • ACROBiosystems
    • antibodies-online
    • The native Antigen Company
    • ProSci

Aktuelle Publikationen für unsere SARS-CoV-2 Spike Proteine

Payam, Funari, Scamarcio, Bhalla: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Wu, Wu, Wang, Liu, Chu, Jiang, Kwong, Chow, Li, Chen: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).

Arunachalam, Feng, Ashraf, Hu, Walls, Edara, Zarnitsyna, Aye, Golden, Miranda, Green, Threeton, Maness, Beddingfield, Bohm, Scheuermann, Goff, Dufour, Russell-Lodrigue, Kepl, Fiala, Wrenn et al.: "Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine. ..." in: Science translational medicine, Vol. 14, Issue 658, pp. eabq4130, (2022) (PubMed).

Schlör, Hirschberg, Amor, Meister, Arora, Pöhlmann, Hoffmann, Pfaender, Eddin, Kamhieh-Milz, Hanack: "SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications." in: Frontiers in immunology, Vol. 13, pp. 930975, (2022) (PubMed).

Funari, Bhalla, Gentile: "Measuring the Radius of Gyration and Intrinsic Flexibility of Viral Proteins in Buffer Solution Using Small-Angle X-ray Scattering." in: ACS measurement science au, Vol. 2, Issue 6, pp. 547-552, (2022) (PubMed).

Aliase für SARS-CoV-2 Spike Proteine

E2 glycoprotein precursor (S) Proteine
Surface Glycoprotein (S) Proteine
E2 Proteine
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