anti-SHC3 (SHC3) Antikörper

Bezeichnung:: anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 Antikörper (SHC3)

Auf www.antikoerper-online.de finden Sie aktuell 62 SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SHC3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 77 SHC3 Produkte verfügbar.

Synonyme:: N-Shc, NSHC, Rai, ShcC

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	SHC3	53358	Q92529
	SHC3	114858
	SHC3	20418	Q61120
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human SHC3 Antikörper:

anti-Rat (Rattus) SHC3 Antikörper:

anti-Mouse (Murine) SHC3 Antikörper:

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Verknüpfte Pathways mit anti-SHC3 Antikörper

Neurotrophin Signalübertragung

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Am meisten referenzierte anti-SHC3 Antikörper

Human Polyclonal SHC3 Primary Antibody für WB - ABIN2801960 : Liu, Meakin: ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. in The Journal of biological chemistry 2002 (PubMed)
Show all 4 Pubmed References

Weitere Antikörper gegen SHC3 Interaktionspartner

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

High SHC3 expression is associated with glioblastoma.
Rai (ShcC/N-Shc), a member of the family of Shc (zeige SHC1 Antikörper)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Polymorphism in RAI (zeige RNH1 Antikörper) and CD3EAP (zeige CD3EAP Antikörper) are associated with outcome of myeloma patients treated with high dose treatment.
amplification of SHC3 and EDG3 (zeige S1PR3 Antikörper) genes suggests that the two proteins co-operate and are important for ependymomas in vivo.
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (zeige SHC1 Antikörper).
ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase.
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret (zeige RET Antikörper) to the phosphatidylinositol 3-kinase/Akt (zeige AKT1 Antikörper) signaling pathway.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (zeige ARHGEF16 Antikörper) cells
The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells.
data suggest that RAI (ShcC/H-Shc (zeige SHC1 Antikörper))is a critical substrate for RET (zeige RET Antikörper) oncoproteins in thyroid carcinomas

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

The results provide evidence that Rai/ShcC plays opposite roles in Th17 cell differentiation and astrocyte activation
Rai (ShcC/N-Shc), a member of the family of Shc (zeige SHC1 Antikörper)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Rai interferes with the TCR signaling cascade one of the earliest steps--recruitment of the initiating kinase ZAP-70 (zeige ZAP70 Antikörper) to the phosphorylated subunit of the TCR/CD3 (zeige CD3E Antikörper) complex.
TrkB (zeige NTRK2 Antikörper)-mediated ERK1/2 activation is impaired in huntingtin (zeige HTT Antikörper) knock-in striatal cells involves reduced p52 (zeige GTF2H4 Antikörper)/p46 (zeige POLDIP3 Antikörper) Shc (zeige SHC1 Antikörper) expression
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (zeige SHC1 Antikörper).
binds the Trk (zeige NTRK1 Antikörper) receptors in a phosphotyrosine-dependent manner via their N-terminal phosphotyrosine binding domain
Rai has a functional neuroprotective role in brain injury, with possible implications in the treatment of stroke
ShcC mediates TrkB (zeige NTRK2 Antikörper)-Ras/MAPK (zeige MAPK1 Antikörper) signaling & regulates NMDA receptor function in the hippocampus via interaction with phosphotyrosines on the receptor subunits. It serves as a modulator of hippocampal synaptic plasticity underlying learning & memory.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (zeige ARHGEF16 Antikörper) cells
Expressed in T and B cells; loss of Rai results in breaking of immunological tolerance and development of systemic autoimmunity.

SHC3 Antigen-Profil

Beschreibung des Gens

may be involved in brain-derived neurotrophic factor signalling during retinal development

Alternative names and synonyms associated with SHC3

SHC adaptor protein 3 (SHC3) Antikörper
SHC adaptor protein 3 (Shc3) Antikörper
src homology 2 domain-containing transforming protein C3 (Shc3) Antikörper

N-Shc Antikörper
NSHC Antikörper
Rai Antikörper
ShcC Antikörper

Bezeichner auf Proteinebene für SHC3

SH2 domain protein C3 , SHC-transforming protein 3 , SHC-transforming protein C , neuronal Shc , protein Rai , src homology 2 domain-containing transforming protein C3 , src homology 2 domain-containing-transforming protein C3 , N-Shc

GENE ID	SPEZIES
100061926	Equus caballus
53358	Homo sapiens
114858	Rattus norvegicus
476352	Canis lupus familiaris
20418	Mus musculus

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Show all anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antikörper with Pubmed References

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with SHC3

Bezeichner auf Proteinebene für SHC3