ERBB3 ELISA Kit

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Recommendations are based on data provided indicating:
  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiment Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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ERBB3 Antigen Profile

Beschreibung des Gens

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • erb-b2 receptor tyrosine kinase 3 (ERBB3) ELISA Kit
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) ELISA Kit
  • erb-b2 receptor tyrosine kinase 3 (Erbb3) ELISA Kit
  • ErbB-3 ELISA Kit
  • HER3 ELISA Kit
  • LCCS2 ELISA Kit
  • MDA-BF-1 ELISA Kit
  • c-erbB-3 ELISA Kit
  • c-erbB3 ELISA Kit
  • erbB3-S ELISA Kit
  • p180-ErbB3 ELISA Kit
  • p45-sErbB3 ELISA Kit
  • p85-sErbB3 ELISA Kit
  • ERBB3 ELISA Kit
  • C76256 ELISA Kit
  • Erbb-3 ELISA Kit
  • Erbb3r ELISA Kit
  • Her3 ELISA Kit
  • nuc-ErbB3 ELISA Kit

Bezeichner auf Proteinebene für ERBB3

proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , avian erythroblastosis oncogene B 3 receptor , c-erbB-3 , glial growth factor receptor , receptor tyrosine kinase , avian erythroblastosis oncogene B 3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

GENE ID SPEZIES
2065 Homo sapiens
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
481105 Canis lupus familiaris
100468735 Ailuropoda melanoleuca
13867 Mus musculus
29496 Rattus norvegicus
100712946 Cavia porcellus
100059216 Equus caballus
785655 Bos taurus
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