anti-DDR1 (DDR1) Antikörper

Bezeichnung:: anti-Discoidin Domain Receptor tyrosine Kinase 1 Antikörper (DDR1)

Auf www.antikoerper-online.de finden Sie aktuell 179 Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antikörper von 0 unterschiedlichen Herstellern. Insgesamt sind aktuell 232 DDR1 Produkte verfügbar.

Synonyme:: 6030432F18, AI323681, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKE

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Maus DDR1	DDR1	12305	Q03146
Anti-Human DDR1	DDR1	780	Q08345
Anti-Ratte DDR1	DDR1	25678
Weitere Synonyme anzeigen

Verknüpfte Pathways mit anti-DDR1 Antikörper

Weitere Produktkategorien zu DDR1 Antikörper

Am meisten referenzierte anti-DDR1 Antikörper

Human Monoclonal DDR1 Primary Antibody für ELISA, WB - ABIN965982 : Foehr, Tatavos, Tanabe, Raffioni, Goetz, Dimarco, De Luca, Bradshaw: Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000 (PubMed)
Show all 4 Pubmed References
Human Monoclonal DDR1 Primary Antibody für ELISA, WB - ABIN969082 : Mohan, Mohan, Wilson: Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea. in Experimental eye research 2001 (PubMed)
Show all 3 Pubmed References
Human Polyclonal DDR1 Primary Antibody für ELISA, WB - ABIN560139 : Turashvili, Bouchal, Baumforth, Wei, Dziechciarkova, Ehrmann, Klein, Fridman, Skarda, Srovnal, Hajduch, Murray, Kolar: Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. in BMC cancer 2007 (PubMed)
Human Polyclonal DDR1 Primary Antibody für IHC (p) - ABIN2478753 : Coakley, Hawkins, Crinis, McManus, Blake, Nordmann, Sloan, Connelly: An unusual case of variegate porphyria with possible homozygous inheritance. in Australian and New Zealand journal of medicine 1990 (PubMed)
Show all 2 Pubmed References
Human Polyclonal DDR1 Primary Antibody für IHC, ELISA - ABIN1847697 : Xu, Abe, Liu, Zalivina, Hohenester, Leitinger: Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implications. in The Journal of biological chemistry 2014 (PubMed)

Weitere Antikörper gegen DDR1 Interaktionspartner

Mouse (Murine) Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

The data suggest that the absence of DDR1 provides a growth and adhesion advantage that favors the expansion of basal cells, potentiates fibrosis, and enhances necrosis/hypoxia and basal differentiation of transformed cells to increase their aggression and metastatic potential.
DDR1 kinase activity is required for regulating collagen IV (zeige COL4 Antikörper) synthesis.
DDR-1 interacts with the TGF-beta (zeige TGFB1 Antikörper) pathway to restrict calcifying extracellular vesicle-mediated mineralization and fibrosis by smooth muscle cells.
alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (zeige ITGA2 Antikörper) DDR1-mediated ERK (zeige EPHB2 Antikörper) activation.
DDR1 malfunction causes outer hair cells deformation and the separation of the lateral wall, the location of the cellular motor responsible for the electromotile property, explicitly in those regions showing DDR1 and NM-IIA co-localization.
the collagen receptors DDR1 and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.
Extensive co-localization and relationship of Jag1 (zeige JAG1 Antikörper) and Ddr1 in bile ducts and blood vessels in postnatal liver.
Genetic inhibition of discoidin domain receptor 1 protects mice against crescentic glomerulonephritis.
Data identifyies Syk (zeige SYK Antikörper) as a potent inhibitor of epithelial migration and describes a first functional consequence of the interaction with the collagen receptor (zeige ITGA2 Antikörper) DDR1.
Results show that DDR1 promotes cell-cell adhesion and differentiation through stabilization of E-cadherin (zeige CDH1 Antikörper), which is mediated by Cdc42 (zeige CDC42 Antikörper) inactivation.

Human Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

These findings demonstrate a critical role of miR (zeige MLXIP Antikörper)-199a-3p/DDR1 pathway in ovarian cancer development.
findings demonstrate that, in human breast cancer cells, DDR1 regulates IR expression and ligand dependent biological actions. This novel functional crosstalk is likely clinically relevant
These results support an activation mechanism of DDR1 whereby collagen induces lateral association of DDR1 dimers and phosphorylation between dimers.
Data suggest that IGF-I (zeige IGF1 Antikörper)/IGF-IR system triggers stimulatory actions through both GPER (zeige GPER Antikörper) and DDR1 in aggressive tumors as mesothelioma and lung tumors.
we further analyzed the CpG methylation levels at the DDR1 promoter in EOC cells and found that the CpG methylation levels of DDR1 promoter correlated negatively with the expression of DDR1 along the EMT (zeige ITK Antikörper) spectrum. Therefore, EMT (zeige ITK Antikörper) stratification could be a potential biomarker to predict patient response to DDR1-targeting drugs.
This study suggested that DDR1 and DDR2 (zeige DDR2 Antikörper) knockdown alters brain immunity and significantly reduces the level of triggering receptor expressed on myeloid cells (TREM)-2 (zeige TREM2 Antikörper) and microglia.
Isoform b of DDR1 is responsible for collagen I-induced up-regulation of N-cadherin (zeige CDH2 Antikörper) and tyrosine 513 of DDR1b is necessary.
Reduced DDR1 expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (zeige MITF Antikörper) pathogenesis
data demonstrate that TGF-beta1 (zeige TGFB1 Antikörper) favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2 (zeige LOXL2 Antikörper), and the components such as DDR1 and MT1-MMP (zeige MMP14 Antikörper) of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1 (zeige TGFB1 Antikörper)-dependent regulation of DDR1 expression.
DDR1 overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.

DDR1 Antigen-Profil

Beschreibung des Gens

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with DDR1

Discoidin domain receptor (Ddr) Antikörper
discoidin domain receptor family, member 1 (Ddr1) Antikörper
discoidin domain receptor tyrosine kinase 1 (DDR1) Antikörper
discoidin domain receptor tyrosine kinase 1 (Ddr1) Antikörper

6030432F18 Antikörper
AI323681 Antikörper
CAK Antikörper
CD167 Antikörper
CD167a Antikörper
CG9488 Antikörper
CG9490 Antikörper
CG11573 Antikörper
CG13984 Antikörper
CG13985 Antikörper
CG33531 Antikörper
CT33540 Antikörper
DDR Antikörper
Dmel\\CG33531 Antikörper
Dmel_CG13984 Antikörper
Drd1 Antikörper
EDDR1 Antikörper
HGK2 Antikörper
MCK10 Antikörper
NEP Antikörper
NTRK4 Antikörper
PTK3 Antikörper
PTK3A Antikörper
PTK3D Antikörper
RTK6 Antikörper
TRKE Antikörper

Bezeichner auf Proteinebene für DDR1

, , , , , , , , , , , , , , , , , , , , , CG33531-PA CG33531-PB Ddr-PA Ddr-PB discoidin domain receptor CD167 antigen-like family member A cell adhesion kinase discoidin receptor tyrosine kinase epithelial discoidin domain receptor 1 epithelial discoidin domain-containing receptor 1 protein-tyrosine kinase MPK-6 tyrosine kinase DDR tyrosine-protein kinase CAK PTK3A protein tyrosine kinase 3A mammary carcinoma kinase 10 neuroepithelial tyrosine kinase neurotrophic tyrosine kinase, receptor, type 4 protein-tyrosine kinase RTK-6 discoidin domain receptor family, member 1 neurotrophic tyrosine kinase receptor type 4 protein-tyrosine kinase 3 protein-tyrosine kinase PTK-3

GENE ID	SPEZIES
3346209	Drosophila melanogaster
12305	Mus musculus
780	Homo sapiens
25678	Rattus norvegicus
100144462	Sus scrofa
462548	Pan troglodytes

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Show all anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antikörper with Pubmed References

Mouse (Murine) Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

Human Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with DDR1

Bezeichner auf Proteinebene für DDR1