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anti-Human BDNF Antikörper:
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Dog (Canine) Polyclonal BDNF Primary Antibody für IHC, WB - ABIN2777093
Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. in Neuroscience research 2008
Show all 7 Pubmed References
Human Polyclonal BDNF Primary Antibody für CyTOF, FACS - ABIN4899237
Xapelli, Bernardino, Ferreira, Grade, Silva, Salgado, Cavadas, Grouzmann, Poulsen, Jakobsen, Oliveira, Zimmer, Malva: Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. in The European journal of neuroscience 2008
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Human Polyclonal BDNF Primary Antibody für ICC, IF - ABIN409162
Atasoy, Dursun, Gezen-Ak, Metin-Armağan, Öztürk, Yılmazer: Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons. in Journal of chemical neuroanatomy 2016
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Human Monoclonal BDNF Primary Antibody für FACS, ICC - ABIN4283827
Lambert, Carlson, Formichella, Sappington, Ahlem, Calkins: Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma. in Frontiers in neuroscience 2017
Human Monoclonal BDNF Primary Antibody für CyTOF, FACS - ABIN4899236
Berzi, Ayata, Cavalcante, Falcone, Candiago, Motta, Bernasconi, Hohlfeld, Mantegazza, Meinl, Farina: BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology. in Journal of neuroimmunology 2008
Human Polyclonal BDNF Primary Antibody für EIA, Func - ABIN115986
Hartog, Dittrich, Pieneman, Jansen, Frankl-Vilches, Lessmann, Lilliehook, Goldman, Gahr: Brain-derived neurotrophic factor signaling in the HVC is required for testosterone-induced song of female canaries. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
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Human Polyclonal BDNF Primary Antibody für EIA, Func - ABIN115985
Miknyoczki, Wan, Chang, Dobrzanski, Ruggeri, Dionne, Buchkovich: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
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Human Monoclonal BDNF Primary Antibody für ICC, ELISA - ABIN1724944
Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder. in PLoS ONE 2012
functional interaction between BDNF/TrkB (zeige NTRK2 Antikörper) and PTX3 (zeige PITX3 Antikörper) enhances the osteolysis of bone metastatic gastric cancer.
Study found that the BDNF gene Val66Met polymorphism was associated with hippocampal volume and cortical surface area and cortical thickness in frontal, temporal, and occipital cortices in school-aged children.
Our study shows that carriers of the BDNF Met allele are more vulnerable to the impact of prolonged wakefulness and the biological night on a critical component of executive function, as measured by response inhibition on the Stroop task.
BDNF rs6265 polymorphisms modulate entorhinal cortex-interconnected clusters and the valine allele was associated with stronger structural covariance patterns that determined the cognitive outcomes.
Older patients with bipolar disorder (BD) have lower serum levels of BDNF compared with similarly aged comparators. These effects appear to be specific to patients with BD type I.
Depression level of patients with asthma, negatively correlated with BDNF mRNA expression.
Data show that rs6265, rs11030104 and rs10767664 in brain derived neurotrophic factor (BDNF) were associated with a decreased risk of heroin addiction.
Serum BDNF levels seem to be one of the indicators of schizophrenia and its progress; nevertheless, we still do not have sufficient information about this neurotropic factor
BDNF G196A variant plays a major role in ischemic stroke occurrence and consequences in Iranian patients.
These findings suggest that no significant association exists between attempted suicide and BDNF level.
Orthopedic surgery modulates the expression of neuropeptide Y (zeige NPY Antikörper) and BDNF at the spinal and hippocampal levels.
treating BACHD cortical neurons with ApiCCT1 prevented BACHD striatal neuronal atrophy by enhancing release of BDNF that subsequently acts through tyrosine receptor kinase B (TrkB (zeige NTRK2 Antikörper)) receptor on striatal neurons. Our findings are evidence that TRiC (zeige MARVELD2 Antikörper) reagent-mediated reductions in mHTT enhanced BDNF delivery to restore the trophic status of BACHD striatal neurons.
BDNF in the lower parts of the auditory system drives auditory fidelity along the entire ascending pathway up to the cortex by increasing inhibitory strength in behaviorally relevant frequency regions.
Results highlight the biological significance of alternative brain-derived neurotrophic factor transcripts and provide evidence that individual isoforms serve distinct molecular and behavioral functions.
A critical period of susceptibility to cigarette smoke exposure exists in the prenatal and early postnatal period, which results a downregulation in brain-derived neurotrophic factor/tyrosine kinase receptor B (zeige NTRK2 Antikörper) signaling in the hippocampus and enhances depression-like behaviors later in life.
Deletion of Bdnf in DRG neurons leads to a temporary dysregulation of miR-1.
Excitatory synaptic activation-dependent up-regulation of XBP1 (zeige XBP1 Antikörper) directly facilitated transcriptional activation of BDNF. BDNF in turn drove its own expression via IRE1 (zeige ERN1 Antikörper)-XBP1 (zeige XBP1 Antikörper) pathway in a protein kinase A-dependent manner. Exogenous treatment with BDNF promoteSynaptic activity- and BDNF-dependent distinct activation of dendritic IRE1 (zeige ERN1 Antikörper)-XBP1 (zeige XBP1 Antikörper) cascade drives BDNF expression in cell soma and may be involved in dendritic extension.
We hypothesize that BDNF in the developing brain regulates fear circuit plasticity during a sensitive period in early adolescence, and alterations in BDNF expression (genetic or environmental) have a persistent impact on fear behavior and fear-related disorders.
High BDNF expression is associated with neuropathic pain.
The authors show that BDNF acts cell autonomous and autocrine, as wildtype neurons are not capable of rescuing growth deficits in neighboring MeCP2 deficient neurons in vitro and in vivo.
One of the modulators of TOR (zeige FRAP1 Antikörper) is brain-derived neurotrophic factor (BDNF), which activates the TOR (zeige FRAP1 Antikörper) signaling pathway to promote protein synthesis, synapse strengthening, and the creation of new neural networks.findings demonstrate that TOR (zeige FRAP1 Antikörper) activation in old animals occurs in the early phase of consolidation, and follows a pattern identical to that of BDNF expression.
These results suggest an involvement of the BDNF/TrkB (zeige NTRK2 Antikörper) system in the regulation of food intake and energy balance in zebrafish, as in mammals
BDNF-TrkB (zeige NTRK2 Antikörper) influences the expression level of components of chemokine (zeige CCL1 Antikörper) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (zeige NTRK2 Antikörper) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (zeige RACGAP1 Antikörper) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (zeige PARD3 Antikörper)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (zeige NTRK2 Antikörper) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (zeige HTT Antikörper) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (zeige MAG Antikörper) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (zeige POMC Antikörper)-derived alphaMSH (zeige POMC Antikörper), and that the light controls the biosynthesis and secretion of BDNF and of POMC (zeige POMC Antikörper) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (zeige MMP9 Antikörper) and MMP-2 (zeige MMP2 Antikörper), caspase-3 (zeige CASP3 Antikörper) and BDNF
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (zeige INS Antikörper) and leptin (zeige LEP Antikörper).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Study showed that complex relationships exist between BDNF/TrkB (zeige NTRK2 Antikörper) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (zeige Arc Antikörper) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
, brain derived neurothrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain-derived neurotrophic factor
, neurotrophic factor