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Human Polyclonal TRERF1 Primary Antibody für IHC (p), IP - ABIN257099 : Bantscheff, Hopf, Savitski, Dittmann, Grandi, Michon, Schlegl, Abraham, Becher, Bergamini, Boesche, Delling, Dümpelfeld, Eberhard, Huthmacher, Mathieson, Poeckel, Reader, Strunk, Sweetman, Kruse et al.: Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. ... in Nature biotechnology 2011 (PubMed)
TReP-132 plays a role in regulating p450scc (zeige CYP11A1 Antikörper) expression with steroidogenic factor-1 (zeige NR5A1 Antikörper) and CBP/p300 (zeige CREBBP Antikörper)
TReP-132 interacts with steroidogenic factor-1 (SF-1 (zeige NR5A1 Antikörper)) through specific domains; and along with the interaction with CBP/p300 (zeige CREBBP Antikörper) these factors are postulated to form a complex to regulate expression of the P450scc (zeige CYP11A1 Antikörper) gene.
TReP-132 is a trans-acting factor of genes involved in adrenal glucocorticoid, C(19) steroid and estrogen production.
TReP-132 is a basal cell cycle regulatory protein (zeige RCC1 Antikörper) interacting with Sp1 (zeige PSG1 Antikörper) to activate the p21 (zeige CDKN1A Antikörper) and p27 (zeige PAK2 Antikörper) gene promoters.
identify TReP-132 as a coactivator of progesterone receptor (zeige PGR Antikörper) mediating the growth-inhibitory and differentiation effects of progesterone on breast cancer cells
cloning and characterization; expression of both mTReP-132 and P450scc (zeige CYP11A1 Antikörper) provides anatomical evidence that mTReP-132 may regulate this key steroidogenic enzyme within specific regions of the brain involved in behavioral and psychiatric disorders
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.
breast cancer anti-estrogen resistance 2 , rapa-1 , rapa-2 , transcriptional regulating protein 132 , transcriptional-regulating factor 1 , transcriptional-regulating protein 132 , zinc finger protein rapa , zinc finger transcription factor TReP-132 , transcriptional regulating factor 1