anti-Guanylate Cyclase Activator 1A (Retina) Antikörper
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anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 1-93) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (C-Term) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 160-191), (C-Term) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (C-Term) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (N-Term) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 1-93) Antikörper Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 36-85) Antikörper Primary Antibody
Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antigen-Profil
Protein Überblick
This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations. GCAP1 promotes activity of GC1 at low Ca(2+) concentrations and inhibits GC1 activity at high Ca(2+) concentrations. Mutations in this gene cause autosomal dominant cone dystrophy (COD3)\; a disease characterized by reduced visual acuity associated with progressive loss of color vision. Mutations in this gene prohibit the inactivation of RetGC1 at high Ca(2+) concentrations\; causing the constitutive activation of RetGC1 and, presumably, increased cell death. This gene is expressed in retina and spermatagonia.
Alternative names and synonyms associated with Guanylate Cyclase Activator 1A (Retina) (GUCA1A)
- guanylate cyclase activator 1A (GUCA1A) Antikörper
- guanylate cyclase activator 1A (Guca1a) Antikörper
- guanylate cyclase activator 1A L homeolog (guca1a.L) Antikörper
- guanylate cyclase activator 1A (retina) (guca1a) Antikörper
- guanylate cyclase activator 1a (retina) (Guca1a) Antikörper
- guanylate cyclase activator 1A (guca1a) Antikörper
- C6orf131 Antikörper
- COD3 Antikörper
- CORD14 Antikörper
- dJ139D8.6 Antikörper
- GC-A Antikörper
- GCAP Antikörper
- gcap1 Antikörper
- GUCA Antikörper
- Guca1 Antikörper
- guca1a Antikörper
- MGC84170 Antikörper
- MGC146317 Antikörper
- mGCAP1 Antikörper
Bezeichner auf Proteinebene für GUCA1A
GCAP 1 , cone dystrophy 3 , guanylate cyclase-activating protein, photoreceptor 1 , guanylin 1, retina , guanylyl cyclase-activating protein 1 , guanylate cyclase activator 1A (retina)
| GENE ID | SPEZIES |
|---|---|
| 2978 | Homo sapiens |
| 282243 | Bos taurus |
| 301233 | Rattus norvegicus |
| 374216 | Gallus gallus |
| 444645 | Xenopus laevis |
| 609180 | Canis lupus familiaris |
| 748651 | Pan troglodytes |
| 779962 | Xenopus (Silurana) tropicalis |
| 100224057 | Taeniopygia guttata |
| 14913 | Mus musculus |
| 100715154 | Cavia porcellus |
| 140430 | Danio rerio |
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