Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human TMSB4X Antikörper:
anti-Mouse (Murine) TMSB4X Antikörper:
anti-Rat (Rattus) TMSB4X Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Monoclonal TMSB4X Primary Antibody für ELISA, WB - ABIN1327173
Martin-Lorenzo, Balluff, Maroto, Carreira, van Zeijl, Gonzalez-Calero, de la Cuesta, Barderas, Lopez-Almodovar, Padial, McDonnell, Vivanco, Alvarez-Llamas: Molecular anatomy of ascending aorta in atherosclerosis by MS Imaging: Specific lipid and protein patterns reflect pathology. in Journal of proteomics 2015
Tbeta4 in the early fetal heart is primarily localised to endothelial cells of the cardiac microvasculature and coronary vessels as well as to the endothelial-like cells of the endocardium and to the epicardium.
TMSB4X was highly expressed at both RNA and protein level in head and neck squamous cell carcinoma (HNSCC) tumor samples and significantly associated with poor overall and recurrence-free survivals in HNSCC patients. Its overexpression in HNSCC cell line reduced the proliferation and invasion ability.
Serum Tbeta4 level can be used as a biomarker for the diagnosis of NASH and was negatively correlated with the oxidation state of the liver
we suggest that overexpression of Tbeta4 might play a role in the progression of gastric gastrointestinal stromal tumors
Tbeta4 exerts a protective effect on murine colitis, indicating that recombinant adeno-associated virus carrying thymosin beta4 could potentially be developed into a promising agent for the therapy of inflammatory bowel diseases.
Results showed that the TMSB4 pseudogene, lncRNA-MSR, was upregulated in the damaged cartilage and was activated in chondrocytes in response to mechanical stress. Furthermore, lncRNA-MSR regulated the expression of TMSB4 by competing with miRNA-152 in chondrocytes.
Tbeta4 gene silencing in A549 and H1299 cells inhibited cell proliferation, migration, and invasion in vitro and decreased tumor growth in vivo. Mechanistic investigations revealed a significant decrease in Notch1 activation in Tbeta4 gene-silenced cells.
Developed an innovative biotechnological method for thymosin beta4 production that employs the peptide acetylation in vivo.
Serum thymosin beta4 concentrations were correlated with the occurrence and severity of obstructive sleep apnea syndrome.
Overexpression of Tbeta4 enhanced cell proliferation and colony formation in oral squamous cell carcinoma.
Tbeta-4 was validated in clinical samples using a tissue microarray to predict overall survival in colon cancer patients
this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.
this study demonstrates, for the first time, that Tbeta4 is expressed in developing periodontal tissue and that its expression is associated with osteoblastic/cementoblastic differentiation.
This article reviews the potential role of thymosin beta 4 in liver fibrosis by describing the effects of exogenous and endogenous thymosin beta 4 , and discusses the possible signaling pathway regulated by TB4X. [review]
The results of the present study suggested that Tb4 may promote HB metastasis via the induction of EMT, and that Tb4 may therefore be a target for the development of novel treatments for patients with Hepatoblastoma .
these results suggest that NO could regulate the expression of Tbeta4 by direct or indirect effect of HIF-1alpha on Tbeta4 promoter.
the exchange of bound actin between Tbeta4 and profilin involves both steric and allosteric components.
Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway.
Regarding HCC, Tbeta4 reactivity was detected in 7/23 cases (30%) and Tbeta10 reactivity in 22/23 (97%) cases analyzed, adding HCC to human cancers that express these beta-thymosins.
Thymosin beta-4 levels in the serum and synovial fluid of knee osteoarthritis patients are significantly correlated with disease severity.
Tb4 induced BSP expression in MDPC23 cells via ERK and Smad3 signaling pathways, suggesting its role as a signaling molecule in odontoblasts for regulating BSP secretion during dentinogenesis.
Tmsb4X was up-regulated in Crybb2 mutant brain. Additionally, Tmsb4X was co-expressed with Crybb2 at actin-enriched cell ruffles. Over-expression of Tmsb4X in cultured hippocampal neurons inhibited dendritogenesis, which phenocopied Crybb2 knock-down.
expressed prominently in podocytes; modifier of glomerular injury
Our data suggest that Tbeta4 is required for setting correct sarcomere length and for appropriate splicing of titin, not only in the heart but also in skeletal muscle.
Increased Tb4 expression was observed in ethanol treated microglia. Knockdown of Tb4 enhanced ethanol-induced inflammatory mediators tumor necrosis factor-alpha and interleukin-1beta and nitric oxide in BV-2 cells was performed.
Results provide evidence that Tbeta4 regulate the levels of VEGF and MMP-2 via the Wnt/beta-catenin/Lef-1 signaling pathway to influence the growth of blood vessels around hair follicles and to activate cell migration.
we identified the C-terminal four amino-acid variable end of TB4 as the essential and responsible domain for the molecule's full benefits in the hypoxic heart.
From the results, Tbeta4 increased the viability and promoted the differentiation and mineralization of MC3T3-E1 cells on Ti discs.
Tbeta4 appears to regulate P38/ERK/AKT signaling via its effect on VEGF expression, with a resultant effect on the speed of hair growth, the pattern of HFs and the number of hair shafts
This study provides putative information concerning the signaling pathway through which Tb4 induces RUNX2 expression, which may help to understand the regulation of tooth development and tooth regeneration.
Tbeta4 substantially inhibited bleomycin-induced IL-17 over-expression in the lung tissue: a decreased amount of IL17-producing cells and inhibited IL-17 expression in lung with Tbeta4 treatment correlate with its anti-inflammatory and anti-fibrotic effects.
The results suggest that Tbeta4 plays multiple functional roles in odontogenic epithelial cells in the early stages of tooth germ development by regulating the expression of odontogenesis-related genes.
Analysis at 21 days post-fracture show that the fractional volume of new mineralized tissue and new highly mineralized tissue are greater in calluses from Tbeta4-treated mice compared to controls.
These data suggest that Tbeta4 suppresses the TLR proinflammatory pathway by up-regulating miR-146a.
Demonstrate that Tbeta4 is dispensable for embryonic viability and vascular development.
Thymosin beta4 may play a role in aging-related hearing loss.
These data show that thymosinbeta4 and beta-actin are over-expressed during nurse cell formation upon T. spiralis infection and may be involved in nurse cell formation along with other actin-binding proteins.
Thymosin beta4 is a novel endothelial secreted trophic factor that functions synergistically with TGFbeta to regulate mural cell development and vascular wall stability.
TMSB4 and/or TMSB10 ovarian expression patterns suggest that these two thymosins may be involved in cumulus modifications during maturation.
Tbeta4 induces apoptotic-related gene expression in leukemic cells, and results in the inhibition of proliferation and induction of differentiation and apoptosis of leukemic cells
expressed at higher levels in articular osteochondrosis than in control cartilage
This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.
, t beta-4
, thymosin beta-4
, thymosin, beta 4, X chromosome
, prothymosin beta 4
, t beta 4
, thymosin beta 4, X-linked
, thymosin beta 4Xen
, thymosin beta 4, X chromosome
, thymosin, beta 4, X-linked
, thymosin, beta 4
, thymosin beta 4 X-linked
, thymosin b4