This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011].
Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: "Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3373-83, (2008) (PubMed).
Aliase für RAP1B Proteine
RAP1B, member of RAS oncogene family (RAP1B) Proteine RAP1B, member of RAS oncogene family (Rap1b) Proteine RAP1B, member of RAS oncogene family L homeolog (rap1b.L) Proteine RAP1B, member of RAS oncogene family (Bm1_39445) Proteine RAS related protein 1b (Rap1b) Proteine ras-related protein Rap-1b-like (LOC109067672) Proteine RAP1B, member of RAS oncogene family (rap1b) Proteine 2810443E11Rik Proteine cb119 Proteine cb1026 Proteine K-REV Proteine k-rev Proteine RAL1B Proteine ral1b Proteine Rap1b Proteine sb:cb119 Proteine wu:fb11c04 Proteine wu:fb74e09 Proteine wu:fk70e05 Proteine