RAB7B Produkte
(RAB7B, Member RAS Oncogene Family (RAB7B))
Kategorien
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway (By similarity).
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Ausgewählte RAB7B Kategorien
RAB7B Antikörper
High quality antibodies with extensive validation data.
RAB7B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RAB7B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP
Validierungen
- (6)
- (6)
Kat. Nr.
ABIN567027
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1881722
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN531617
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene RAB7B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317195
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317197
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3086874
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RAB7B Produkten
: "Rab7a regulates cell migration through Rac1 and vimentin." in: Biochimica et biophysica acta, Vol. 1864, Issue 2, pp. 367-381, (2016) (PubMed).: "A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration." in: Journal of cell science, Vol. 127, Issue 22, pp. 4927-39, (2014) (PubMed).
: "Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells." in: Molecular biology of the cell, Vol. 22, Issue 10, pp. 1699-715, (2011) (PubMed).
: "GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation." in: Journal of neurochemistry, Vol. 115, Issue 2, pp. 423-37, (2010) (PubMed).
: "Rab7b controls trafficking from endosomes to the TGN." in: Journal of cell science, Vol. 123, Issue Pt 9, pp. 1480-91, (2010) (PubMed).
: "SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery." in: Molecular biology of the cell, Vol. 20, Issue 4, pp. 1223-40, (2009) (PubMed).
: "Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 9, pp. 994-1005, (2009) (PubMed).
: "Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells." in: Biochemical and biophysical research communications, Vol. 318, Issue 3, pp. 792-9, (2004) (PubMed).
Synonyme und alternative Namen zu RAB7B
Rab7b, member RAS oncogene family (Rab7b), rab7B protein (rab7B), RAB7B, member RAS oncogene family (RAB7B), RAB7B, member RAS oncogene family S homeolog (rab7b.S), RAB7B, member RAS oncogene family (rab7b), RAB7B, member RAS oncogene family (Rab7b), RAB7, RAB7B, Rab7b, RGD1562617Bezeichner auf Proteinebene für RAB7B
- ras-related protein Rab-7b
- rab7B protein
- RAB7B, member RAS oncogene family
- Ras-related protein Rab-7
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