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RAB7A Produkte

(RAB7A, Member RAS Oncogene Family (RAB7A))

Kategorien

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008].

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Ausgewählte RAB7A Kategorien

RAB7A Antikörper

High quality antibodies with extensive validation data.

RAB7A ELISA Kits

Reliable ELISA kits for a wide range of species.

RAB7A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RAB7A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p), FACS
Validierungen
  • (7)
Kat. Nr. ABIN652609
Menge 400 μL
Datenblatt Datenblatt

Applikation WB, IF
Validierungen
  • (5)
Kat. Nr. ABIN6254195
Menge 600 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF (cc)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN720191
Menge 100 μL
Datenblatt Datenblatt

Empfohlene RAB7A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959032
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951224
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RAB7A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124764
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317193
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7321067
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RAB7A Produkten

Pohar, Lainšček, Ivičak-Kocjan, Cajnko, Jerala, Benčina: "Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9." in: Nature communications, Vol. 8, pp. 15363, (2018) (PubMed).

Pera, Larrea, Guardia-Laguarta, Montesinos, Velasco, Agrawal, Xu, Chan, Di Paolo, Mehler, Perumal, Macaluso, Freyberg, Acin-Perez, Enriquez, Schon, Area-Gomez: "Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease." in: The EMBO journal, Vol. 36, Issue 22, pp. 3356-3371, (2017) (PubMed).

Mascia, Gentile, Izzo, Mollo, De Luca, Bucci, Nitsch, Calì: "Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line." in: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1695-708, (2016) (PubMed).

Aboul Naga, Dithmer, Chitadze, Kabelitz, Lucius, Roider, Klettner: "Intracellular pathways following uptake of bevacizumab in RPE cells." in: Experimental eye research, Vol. 131, pp. 29-41, (2015) (PubMed).

Zhuang, Northup, Ray: "Large putative PEST-like sequence motif at the carboxyl tail of human calcium receptor directs lysosomal degradation and regulates cell surface receptor level." in: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 4165-76, (2012) (PubMed).

Ye, Gao, Tian, Yearsley, Lange, Robertson, Barsky: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).

Cheng, Shih, Huang, Chi, Wu, Liu: "Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules." in: Journal of virology, Vol. 86, Issue 24, pp. 13653-61, (2012) (PubMed).

Meggouh, Bienfait, Weterman, de Visser, Baas: "Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene." in: Neurology, Vol. 67, Issue 8, pp. 1476-8, (2006) (PubMed).

Wu, Wang, Loh, Hong, Song: "Structural basis for recruitment of RILP by small GTPase Rab7." in: The EMBO journal, Vol. 24, Issue 8, pp. 1491-501, (2005) (PubMed).

Verhoeven, De Jonghe, Coen, Verpoorten, Auer-Grumbach, Kwon, FitzPatrick, Schmedding, De Vriendt, Jacobs, Van Gerwen, Wagner, Hartung, Timmerman: "Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy." in: American journal of human genetics, Vol. 72, Issue 3, pp. 722-7, (2003) (PubMed).

Synonyme und alternative Namen zu RAB7A

RAB5A, member RAS oncogene family (RAB5A), RAB7A, member RAS oncogene family (RAB7A), RAB7A, member RAS oncogene family (Rab7a), RAB7A, member RAS oncogene family L homeolog (rab7a.L), RAB7A, member RAS oncogene family (rab7a), rab7A protein (rab7A), RAB GTPase homolog 7A (RAB7A), Rab GTPase (rab7A), ras-related protein rab-7a (rab7a), RAB7, member RAS oncogene family (Rab7), RAB7, member RAS oncogene family (rab7), ARABIDOPSIS RAB GTPASE HOMOLOG G2, ATRAB7A, ATRABG2, DDBDRAFT_0190210, DDBDRAFT_0191507, DDB_0190210, DDB_0191507, F7D8.20, F7D8_20, LOC100231734, PRO2706, pro2706, rab-7, RAB5, RAB7, Rab7, rab7, RAB7A, Rab7a, RAB GTPase homolog 7A, zgc:64058

Bezeichner auf Proteinebene für RAB7A

  • RAS-associated protein RAB5A
  • ras-related protein Rab-5A
  • RAB7, member RAS oncogene family
  • Ras-associated protein RAB7
  • ras-related protein Rab-7a
  • ras-related protein BRL-RAS
  • ras-related protein p23
  • GTP-binding protein (rab7)
  • ras-related protein Rab-7
  • RAB7A, member RAS oncogene family
  • rab7A protein
  • ras-related protein rab-7a
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