Angiostatin Protein (ANG)

Produktnummer ABIN987759

Dieses Recombinant Angiostatin-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Angiostatin Protein (ANG) (ABIN987759)

Target: Angiostatin (ANG)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by SDS-PAGE and HPLC analyses.

Produktdetails

Sequenz: VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSS

Produktmerkmale: Fully biologically active when compared to standard. The activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo. The specific activity of anti-migration of endothelial cells in vitro is 0.55×105 Units/mg.

Endotoxin-Niveau: Level Less than 1EU/µg of rHuAngiostatin as determined by LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Lagerung: 4 °C

Antigendetails

Target: Angiostatin (ANG)

Andere Bezeichnung: Angiostatin K1-3

Hintergrund: Angiostatin K1-3 is a ~30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli. Synonym: Angiostatin K1-3, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.

Molekulargewicht: Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.

Pathways: Lipid Metabolism