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VEGF 165 (Active) Protein

Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935908
  • Target
    VEGF 165
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 20
    • 2
    • 1
    Human
    Quelle
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
    Produktmerkmale
    Purified recombinant Human VEGF165 protein
    Expression System: E.coli
    Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0-8.0 ng/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    VEGF 165
    Andere Bezeichnung
    VEGF165
    Hintergrund
    VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase(flt-1), kDaR gene product (the Mouse homolog of kDaR is the flk-1 gene product) and the flt4 gene product.
    Alternative Names: Folliculostellate cell-derived growth factor protein, Glioma-derived endothelial cell mitogen protein, VEGF-165 protein, Vascular Endothelial Growth Factor protein, VPF protein
    Molekulargewicht
    38.5 kDa
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