VEGFC Protein
Kurzübersicht für VEGFC Protein (ABIN935903)
Target
Alle VEGFC Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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                                            Sequenz
- MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR
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                                            Produktmerkmale
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                        Purified recombinant Human VEGF C protein
 Expression System: HEK cells
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                                            Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
 
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                                            Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Buffer
- Supplied as a lyophilized powder.
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                                            Handhabung
- Avoid repeated freeze/thaw cycles.
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                                            Lagerung
- 4 °C/-20 °C
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                                            Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
 
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    - VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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                                            Andere Bezeichnung
- VEGF C
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                                            Hintergrund
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                        VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. 
 Alternative Names: VRP protein, flt4 ligand protein, Vascular Endothelial Growth Factor-C protein
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                                            Pathways
- RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2
 Target
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