Thrombopoietin Protein (THPO)
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- Target Alle Thrombopoietin (THPO) Proteine anzeigen
- Thrombopoietin (THPO)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
- Produktmerkmale
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Purified recombinant Human Thrombopoietin protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product THPO Protein
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Thrombopoietin (THPO) (AA 22-195) protein (His-IF2DI Tag)
THPO Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) (AA 23-195) protein (His tag)THPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) (AA 22-356) (Active) proteinTHPO Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Thrombopoietin (THPO) protein (His tag)THPO Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Thrombopoietin (THPO) (AA 1-349) protein (GST tag)THPO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Thrombopoietin (THPO) proteinTHPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Lyophilized from 10 mM sodium citrate, pH 3.0.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Thrombopoietin (THPO)
- Andere Bezeichnung
- Thrombopoietin (THPO Produkte)
- Synonyme
- MGDF Protein, MKCSF Protein, ML Protein, MPLLG Protein, THCYT1 Protein, TPO Protein, Mgdf Protein, Ml Protein, Mpllg Protein, Tpo Protein, Tpo1 Protein, Tpo2 Protein, Tpo3 Protein, Tpo4 Protein, tpo Protein, LOC100231762 Protein, thrombopoietin Protein, THPO Protein, Thpo Protein, thpo Protein
- Hintergrund
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TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity.
Alternative Names: TPO protein, THPO protein, MGDF protein, c-MPL Ligand protein, Megakaryocyte colony-stimulating factor protein - Molekulargewicht
- 18.6 kDa
- Pathways
- JAK-STAT Signalweg, Hormone Activity
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