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CCL4 Protein

Dieses Recombinant CCL4-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN935657

Kurzübersicht für CCL4 Protein (ABIN935657)

Target

Alle CCL4 Proteine anzeigen
CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Maus

Quelle

  • 22
  • 5
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % pure
  • Sequenz

    APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN

    Produktmerkmale

    Purified recombinant Mouse MIP1 beta protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 20.0-100.0 ng/mL.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

    Andere Bezeichnung

    MIP1 beta

    Hintergrund

    Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
    Alternative Names: MIP beta 1 protein, MIP beta-1 protein, MIP1 beta, MIP beta-1, ACT-2 protein, MIP-1 beta protein, CCL4 protein, Macrophage Inflammatory Protein-1 beta protein, MIP beta 1

    Molekulargewicht

    7.8 kDa
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