CCL4 Protein

Produktnummer ABIN935657

Dieses Recombinant CCL4-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CCL4 Protein (ABIN935657)

Target: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % pure

Produktdetails

Sequenz: APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN

Produktmerkmale: Purified recombinant Mouse MIP1 beta protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 20.0-100.0 ng/mL.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Andere Bezeichnung: MIP1 beta

Hintergrund: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
Alternative Names: MIP beta 1 protein, MIP beta-1 protein, MIP1 beta, MIP beta-1, ACT-2 protein, MIP-1 beta protein, CCL4 protein, Macrophage Inflammatory Protein-1 beta protein, MIP beta 1

Molekulargewicht: 7.8 kDa