CCL4 Protein (AA 24-92) (Biotin)
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- Target Alle CCL4 Proteine anzeigen
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 24-92
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses CCL4 Protein ist gelabelt mit Biotin.
- Applikation
- Cell Migration Assay (CMA)
- Sequenz
- APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
- Produktmerkmale
- Biotininylated Recombinant Human CCL4 (MIP-1beta)
- Reinheit
- > 97 % by SDS PAGE
- Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.32-1.3 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL4 Protein
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Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein
CCL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (GST tag)CCL4 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 26-92) protein (His tag)Crystallography grade CCL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His tag)Crystallography grade CCL4 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His tag)Crystallography grade CCL4 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Haltbarkeit
- 12 months
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- Target
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
- Andere Bezeichnung
- CCL4 (MIP-1beta) (CCL4 Produkte)
- Synonyme
- ACT2 Protein, AT744.1 Protein, G-26 Protein, HC21 Protein, LAG-1 Protein, LAG1 Protein, MIP-1-beta Protein, MIP1B Protein, MIP1B1 Protein, SCYA2 Protein, SCYA4 Protein, CCL4 Protein, K203 Protein, Mip1-b Protein, Scya4 Protein, MIP-1beta Protein, MIP-1BETA Protein, MIP1b Protein, SCY4A Protein, Act-2 Protein, MIP-1B Protein, Mip1b Protein, ACT-2 Protein, AT744.2 Protein, CCL4L Protein, SCYA4L Protein, SCYA4L1 Protein, SCYA4L2 Protein, C-C motif chemokine ligand 4 Protein, chemokine (C-C motif) ligand 4 Protein, chemokine (C-C motif) ligand 4-like 1 Protein, C-C motif chemokine ligand 4 like 1 Protein, CCL4 Protein, Ccl4 Protein, CCL4L1 Protein
- Hintergrund
- Monokine with inflammatory and chemokinetic properties binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
- Molekulargewicht
- 10.238 kDa
- UniProt
- P13236
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