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CCL4 Protein

CCL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935632
  • Target Alle CCL4 Proteine anzeigen
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Quelle
    • 21
    • 5
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
    Produktmerkmale
    Purified recombinant Human MIP1 beta protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 5.0-20.0 ng/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product CCL4 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Supplied lyophilized with no additives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
    Andere Bezeichnung
    MIP1 beta (CCL4 Produkte)
    Synonyme
    ACT2 Protein, AT744.1 Protein, G-26 Protein, HC21 Protein, LAG-1 Protein, LAG1 Protein, MIP-1-beta Protein, MIP1B Protein, MIP1B1 Protein, SCYA2 Protein, SCYA4 Protein, CCL4 Protein, K203 Protein, Mip1-b Protein, Scya4 Protein, MIP-1beta Protein, MIP-1BETA Protein, MIP1b Protein, SCY4A Protein, Act-2 Protein, MIP-1B Protein, Mip1b Protein, ACT-2 Protein, AT744.2 Protein, CCL4L Protein, SCYA4L Protein, SCYA4L1 Protein, SCYA4L2 Protein, C-C motif chemokine ligand 4 Protein, chemokine (C-C motif) ligand 4 Protein, chemokine (C-C motif) ligand 4-like 1 Protein, C-C motif chemokine ligand 4 like 1 Protein, CCL4 Protein, Ccl4 Protein, CCL4L1 Protein
    Hintergrund
    Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
    Alternative Names: MIP beta-1 protein, MIP beta 1, MIP beta-1, ACT-2 protein, CCL4 protein, Macrophage Inflammatory Protein-1 beta protein, MIP-1 beta protein, MIP1 beta, MIP beta 1 protein
    Molekulargewicht
    7.8 kDa
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