TNFSF14 Protein
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- Target Alle TNFSF14 Proteine anzeigen
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
- Produktmerkmale
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Purified recombinant Human LIGHT protein
Expression System: E.coli - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TNFSF14 Protein
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Abstract
- TNFSF14 Produkte
- Synonyme
- TNFSF14 Protein, CD258 Protein, HVEML Protein, LIGHT Protein, LTg Protein, TR2 Protein, HVEM-L Protein, Ly113 Protein, TNF superfamily member 14 Protein, tumor necrosis factor (ligand) superfamily, member 14 Protein, TNFSF14 Protein, Tnfsf14 Protein
- Hintergrund
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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
Alternative Names: TNFSF14 protein, HVEM-L protein, TNF14 protein, Ligand for herpesvirus entry mediator protein, CD258 protein - Molekulargewicht
- 20.1 kDa
- Pathways
- Cancer Immune Checkpoints
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