TNFSF14 Protein
Kurzübersicht für TNFSF14 Protein (ABIN935610)
Target
Alle TNFSF14 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV
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Produktmerkmale
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Purified recombinant Human LIGHT protein
Expression System: Hi-5 cells -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 16.256,82 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 18.117,43 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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Hintergrund
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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
Alternative Names: CD258 protein, Ligand for herpesvirus entry mediator protein, TNF14 protein, TNFSF14 protein, HVEM-L protein -
Molekulargewicht
- 19.3 kDa
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Pathways
- Cancer Immune Checkpoints
Target
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