FGF7 Protein

Produktnummer ABIN935597

Dieses Recombinant FGF7-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für FGF7 Protein (ABIN935597)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % pure

Produktdetails

Sequenz: MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT

Produktmerkmale: Purified recombinant Human KGF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ? 10 ng/mL, corresponding to a specific activity of ? 1 x 10^5 units/mg.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS to a concentration of 0.5-1.0 mg/mL.

Buffer: Lyophilized from 15 mM Na3PO4 with 0.25 M NaCl, pH7.0.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Andere Bezeichnung: KGF

Hintergrund: Keratinocyte Growth Factor (KGF/FGF7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF7 plays a role in kidney and lung development, angiogenesis, and wound healing.
Alternative Names: Keratinocyte Growth Factor protein, HBGF-7 protein, Fibroblast Growth Factor-7 protein

Molekulargewicht: 18.9 kDa

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung