CCL2 Protein

Produktnummer ABIN935595

Dieses Recombinant CCL2-Protein wird in Escherichia coli (E. coli) exprimiert und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CCL2 Protein (ABIN935595)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN

Produktmerkmale: Purified recombinant Mouse MCP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/mL.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water to 0.1-1.0 mg/mL. Allow to set for at least 30 minutes.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Referenzen

Bogen, Dina, Gear, Levine: "Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican." in: Neuroscience, Vol. 159, Issue 2, pp. 780-6, (2009) (PubMed).

Frøyland, Pedersen, Kvissel, Almaas, Pharo, Skålhegg, Mollnes, Rootwelt: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).

Antigendetails

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Andere Bezeichnung: MCP1

Hintergrund: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species.
Alternative Names: MCP-1 protein, MCP 1, MCP1, MCP-1 protein, MCP-1 protein, MCP 1 protein, Monocyte Chemotactic Protein-1 protein, MCP-1, CCL2 protein

Molekulargewicht: 13.8 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylierungen bei SARS-CoV-2 Infektion