IL-4 Protein
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- Target Alle IL-4 (IL4) Proteine anzeigen
- IL-4 (IL4) (Interleukin 4 (IL4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Ratte
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
- Produktmerkmale
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Purified recombinant Rat IL4 protein
Expression System: E.coli
Bioactivity: Tested by its ability to suppress LPS-induced TNF-alpha and MIP-2 production in mouse splenocytes. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL4 Protein
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Interleukin 4 (IL4) (AA 25-153) protein
IL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 (IL4) (AA 25-153) protein (His tag)IL4 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 (IL4) (AA 25-153) protein (His-Avi Tag,Biotin)IL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 4 (IL4) (AA 23-140) (Active) proteinIL4 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 4 (IL4) (AA 25-153) protein (His-Avi Tag)IL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 4 (IL4) (AA 25-153) (Active) proteinIL4 Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 4 (IL4) (AA 25-153) (Active) protein (His tag,AVI tag,Biotin)IL4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 4 (IL4) protein (His tag)IL4 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 4 (IL4) (AA 63-153) protein (GST tag)IL4 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 4 (IL4) (AA 25-153) protein (mFc Tag)IL4 Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- IL-4 (IL4) (Interleukin 4 (IL4))
- Andere Bezeichnung
- IL4 (IL4 Produkte)
- Hintergrund
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IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.
Alternative Names: B cell stimulating factor protein, IL 4, BCDF protein, IL-4, Interleukin 4 protein, BSF-1 protein, IL 4 protein, IL-4 protein, IL4, BCGF protein, IL-4 protein - Molekulargewicht
- 14.0 kDa
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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