Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IL-21 Protein

IL21 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935584
  • Target Alle IL-21 (IL21) Proteine anzeigen
    IL-21 (IL21) (Interleukin 21 (IL21))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 40
    • 16
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 37
    • 16
    • 6
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
    Produktmerkmale
    Purified recombinant Mouse IL21 protein
    Expression System: E.coli
    Bioactivity: Determined by a cell proliferation assay using modified Ba/F3 cells. The expected ED50for this effect is 10-50 ng/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL21 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IL-21 (IL21) (Interleukin 21 (IL21))
    Andere Bezeichnung
    IL21 (IL21 Produkte)
    Hintergrund
    IL21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL4 of IgG production, and induction of apoptotic effects in naive B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL21 exerts its effect through binding to a specific type I cytokine receptor, IL21R, which also contains the gamma chain (?c) found in other cytokine receptors including IL2, IL4, IL7, IL9 and IL15.
    Alternative Names: IL-21 protein, IL21, IL-21, IL-21 protein, IL 21 protein, Interleukin 21 protein, IL 21
    Molekulargewicht
    15 kDa
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Sie sind hier:
Kundenservice