IGFBPI Protein

Produktnummer ABIN935566

Produktdetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN

Produktmerkmale: Purified recombinant Human IGF BP1 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ? 0.5 µg/mL in the presence of 6 ng/mL of human IGF-I.

Reinheit: > 97 % pure

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Andere Bezeichnung: IGF BP1 (IGFBPI Produkte)

Synonyme: cb656 Protein, igfbp1 Protein, IGFBP-1 Protein, MGC68538 Protein, afbp Protein, ibp1 Protein, pp12 Protein, igf-bp25 Protein, higfbp-1 Protein, IGFBP1 Protein, LOC100223208 Protein, LOC100305121 Protein, AFBP Protein, IBP1 Protein, IGF-BP25 Protein, PP12 Protein, hIGFBP-1 Protein, IGFBA Protein, insulin like growth factor binding protein 1 Protein, insulin-like growth factor binding protein 1a Protein, insulin like growth factor binding protein 1 S homeolog Protein, insulin like growth factor binding protein 1 L homeolog Protein, insulin-like growth factor binding protein 1 Protein, IGFBP1 Protein, igfbp1a Protein, igfbp1.S Protein, igfbp1.L Protein, igfbp1 Protein, LOC100305121 Protein, Igfbp1 Protein

Hintergrund: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity.
Alternative Names: IGF BP-1, IGF BP-1 protein, IGF BP 1 protein, PP12 protein, IGF BP 1, IBP-1 protein, IGF BP1, Insulin-like Growth Factor-Binding Protein 1 protein, IGF BP-1 protein, Placenta Protein 12 protein

Molekulargewicht: 25.4 kDa

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding