IGFBPI Protein
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- Target Alle IGFBPI Proteine anzeigen
- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
- Produktmerkmale
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Purified recombinant Human IGF BP1 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ? 0.5 µg/mL in the presence of 6 ng/mL of human IGF-I. - Reinheit
- > 97 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IGFBPI Protein
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
- Andere Bezeichnung
- IGF BP1 (IGFBPI Produkte)
- Hintergrund
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity.
Alternative Names: IGF BP-1, IGF BP-1 protein, IGF BP 1 protein, PP12 protein, IGF BP 1, IBP-1 protein, IGF BP1, Insulin-like Growth Factor-Binding Protein 1 protein, IGF BP-1 protein, Placenta Protein 12 protein - Molekulargewicht
- 25.4 kDa
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
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