IGFBPI Protein
Kurzübersicht für IGFBPI Protein (ABIN935566)
Target
Alle IGFBPI Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
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Produktmerkmale
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Purified recombinant Human IGF BP1 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ? 0.5 µg/mL in the presence of 6 ng/mL of human IGF-I. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-259) protein (His tag)
IGFBPI Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 1-259) protein (GST tag)IGFBPI Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) protein (His tag)IGFBPI Spezies: Human Wirt: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
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Andere Bezeichnung
- IGF BP1
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Hintergrund
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity.
Alternative Names: IGF BP-1, IGF BP-1 protein, IGF BP 1 protein, PP12 protein, IGF BP 1, IBP-1 protein, IGF BP1, Insulin-like Growth Factor-Binding Protein 1 protein, IGF BP-1 protein, Placenta Protein 12 protein -
Molekulargewicht
- 25.4 kDa
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Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
Target
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