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IGFBP6 Protein

IGFBP6 Spezies: Human Wirt: Hi-5 Cells Recombinant > 95 % pure Active
Produktnummer ABIN935551
  • Target Alle IGFBP6 Proteine anzeigen
    IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    Human
    Quelle
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Hi-5 Cells
    Sequenz
    RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
    Produktmerkmale
    Purified recombinant Human IGF BP6 protein
    Expression System: Hi-5 cells
    Bioactivity: Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 - 0.4 µg/mL.
    Reinheit
    > 95 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IGFBP6 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Kommentare

    Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
    Andere Bezeichnung
    IGF BP6 (IGFBP6 Produkte)
    Synonyme
    IBP6 Protein, IGFBP-6 Protein, IGF-BP6 Protein, RBP6A Protein, IGFBP6 Protein, igfbp6 Protein, insulin like growth factor binding protein 6 Protein, insulin-like growth factor binding protein 6 Protein, IGFBP6 Protein, Igfbp6 Protein, IGFBP-6 Protein, igfbp6 Protein
    Hintergrund
    IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6 is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid, and specifically inhibits IGF-II actions. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
    Alternative Names: IGF BP-6 protein, IBP-6 protein, IGF BP 6, IGF BP6, IGF BP 6 protein, IGF BP-6 protein, IGF BP-6
    Molekulargewicht
    22.6 kDa
    Pathways
    WNT Signalweg, Myometrial Relaxation and Contraction
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