IGFBP6 Protein
Kurzübersicht für IGFBP6 Protein (ABIN935551)
Target
Alle IGFBP6 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
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Produktmerkmale
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Purified recombinant Human IGF BP6 protein
Expression System: Hi-5 cells
Bioactivity: Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 - 0.4 µg/mL. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)
IGFBP6 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 28-240) protein (His-IF2DI Tag)IGFBP6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 1-240) protein (GST tag)IGFBP6 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 26-238) protein (His tag)IGFBP6 Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)IGFBP6 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (Active) protein (His tag)IGFBP6 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 28-240) protein (His tag)IGFBP6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % SDS
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
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Andere Bezeichnung
- IGF BP6
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Hintergrund
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6 is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid, and specifically inhibits IGF-II actions. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
Alternative Names: IGF BP-6 protein, IBP-6 protein, IGF BP 6, IGF BP6, IGF BP 6 protein, IGF BP-6 protein, IGF BP-6 -
Molekulargewicht
- 22.6 kDa
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Pathways
- WNT Signalweg, Myometrial Relaxation and Contraction
Target
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