Interferon gamma Protein (IFNG)
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- Target Alle Interferon gamma (IFNG) Proteine anzeigen
- Interferon gamma (IFNG)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
- Produktmerkmale
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Purified recombinant Human IFN gamma protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/mL. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product IFNG Protein
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Interferon gamma (IFNG) protein (His-Avi Tag)
IFNG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interferon gamma (IFNG) protein (His-Avi Tag,Biotin)IFNG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Interferon gamma (IFNG) (Active) proteinIFNG Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon gamma (IFNG) (AA 23-155) (Active) proteinIFNG Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by reducing SDS-PAGE. Active
Interferon gamma (IFNG) proteinIFNG Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma (IFNG) (AA 24-166) protein (His tag)IFNG Spezies: Schwein Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon gamma (IFNG) (AA 1-144) protein (His tag)IFNG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon gamma (IFNG) (AA 24-174) protein (His tag)IFNG Spezies: Hamster Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon gamma (IFNG) (Active) protein (Fc Tag)IFNG Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in water to a concentration of 1.0 mg/mL.
- Buffer
- Lyophilized from 10 mM NaPO4, pH 7.4.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- Interferon gamma (IFNG)
- Andere Bezeichnung
- IFN gamma (IFNG Produkte)
- Hintergrund
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IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells.
Alternative Names: IFN-g protein, T cell interferon protein, type II interferon protein, IFN g protein, Immune Interferon protein, MAF protein, Interferon gamma protein - Molekulargewicht
- 16.7 kDa
- Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
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