Interferon gamma Protein (IFNG)

Produktnummer ABIN935522

Dieses Recombinant Interferon gamma-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Interferon gamma Protein (IFNG) (ABIN935522)

Target: Interferon gamma (IFNG)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ

Produktmerkmale: Purified recombinant Human IFN gamma protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/mL.

Endotoxin-Niveau: < 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 1.0 mg/mL.

Buffer: Lyophilized from 10 mM NaPO4, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFN gamma

Hintergrund: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells.
Alternative Names: IFN-g protein, T cell interferon protein, type II interferon protein, IFN g protein, Immune Interferon protein, MAF protein, Interferon gamma protein

Molekulargewicht: 16.7 kDa

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie