IL-17 Protein
Kurzübersicht für IL-17 Protein (ABIN935482)
Target
Alle IL-17 (IL17) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
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Produktmerkmale
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Purified recombinant Human IL17 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/mL. Assay #2: Measured by its ability to induce IL-6 production by NHDF cells. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
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Buffer
- Supplied lyophilized with no additives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IL-17 (IL17) (Interleukin 17 (IL17))
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Andere Bezeichnung
- IL17
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Hintergrund
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The originally described IL17 protein, now known as IL17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.
Alternative Names: IL-17, Interleukin 17 protein, IL-17 protein, IL17, IL 17, CTLA-8 protein, IL-17 protein, IL 17 protein -
Molekulargewicht
- 31 kDa
Target
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