IL-17 Protein

Produktnummer ABIN935482

Recombinant IL-17-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IL-17 Protein (ABIN935482)

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA

Produktmerkmale: Purified recombinant Human IL17 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/mL. Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Andere Bezeichnung: IL17

Hintergrund: The originally described IL17 protein, now known as IL17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.
Alternative Names: IL-17, Interleukin 17 protein, IL-17 protein, IL17, IL 17, CTLA-8 protein, IL-17 protein, IL 17 protein

Molekulargewicht: 31 kDa