G-CSF Protein
Kurzübersicht für G-CSF Protein (ABIN935376)
Target
Alle G-CSF (CSF3) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
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Produktmerkmale
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Purified recombinant Human GCSF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse M-NFS-60 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 5 mM sodium citrate, pH 4.0.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
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Andere Bezeichnung
- GCSF
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Hintergrund
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G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and Mouse G-CSF are cross-species reactive.
Alternative Names: CSF-3 protein, Granulocyte Colony-Stimulating Factor protein, GM-CSF beta protein, MGI-1G protein, pluripoietin protein -
Molekulargewicht
- 18.7 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
Target
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