Epigen Protein

Produktnummer ABIN935330

Dieses Recombinant Epigen-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Epigen Protein (ABIN935330)

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

Produktmerkmale: Purified recombinant Human Epigen protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/mL.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Andere Bezeichnung: Epigen

Hintergrund: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
Alternative Names: EPG protein, Epithelial mitogen protein

Molekulargewicht: 7.9 kDa

Pathways: RTK Signalweg, EGFR Signaling Pathway