Target Alle DLL4 Proteine anzeigen: DLL4 (delta-Like 4 (DLL4))
Protein-Typ: Recombinant
Biologische Aktivität: Active
Spezies 12 5 3: Human
Quelle 8 7 2 1 1: HEK-293T Cells
Sequenz: SGVFQLQLQE FINERGVLAS GRPCEPGCRT FFRVCLKHFQ AVVSPGPCTF GTVSTPVLGT NSFAVRDDSS GGGRNPLQLP FNFTWPGTFS LIIEAWHAPG DDLRPEALPP DALISKIAIQ GSLAVGQNWL LDEQTSTLTR LRYSYRVICS DNYYGDNCSR LCKKRNDHFG HYVCQPDGNL SCLPGWTGEY CQQPICLSGC HEQNGYCSKP AECLCRPGWQ GRLCNECIPH NGCRHGTCST PWQCTCDEGW GGLFCDQDLN YCTHHSPCKN GATCSNSGQR SYTCTCRPGY TGVDCELELS ECDSNPCRNG GSCKDQEDGY HCLCPPGYYG LHCEHSTLSC ADSPCFNGGS CRERNQGANY ACECPPNFTG SNCEKKVDRC TSNPCANGGQ CLNRGPSRMC RCRPGFTGTY CELHVSDCAR NPCAHGGTCH DLENGLMCTC PAGFSGRRCE VRTSIDACAS SPCFNRATCY TDLSTDTFVC NCPYGFVGSR CEFPVGLP
Produktmerkmale: Purified recombinant Human sDLL4 protein
Expression System: 293 cells
Bioactivity: The sDLL-4, when immobilized at concentrations >1.5 µg/mL will inhibit myogenesis in C2C12 cells.
Reinheit: > 95 % pure
Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).
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delta-Like 4 (DLL4) (AA 27-524) protein (His-Avi Tag,Biotin)

DLL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

delta-Like 4 (DLL4) (AA 27-524) protein (Fc Tag)

DLL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

delta-Like 4 (DLL4) (AA 558-685) protein (His-IF2DI Tag)

DLL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA

delta-Like 4 (DLL4) (AA 1-532) (Active) protein (Fc Tag)

DLL4 Spezies: Maus Wirt: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active

delta-Like 4 (DLL4) (AA 27-524) protein (His tag)

DLL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

delta-Like 4 (DLL4) (AA 1-529) (Active) protein (Fc Tag)

DLL4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active

delta-Like 4 (DLL4) (AA 27-529), (active Mutant) protein (Fc Tag)

DLL4 Spezies: Human, Maus Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE)

delta-Like 4 (DLL4) protein (His tag)

DLL4 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

delta-Like 4 (DLL4) protein (His tag)

DLL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

delta-Like 4 (DLL4) (AA 173-518) protein (His tag,GST tag)

DLL4 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen: Nur für Forschungszwecke einsetzbar

Target: DLL4 (delta-Like 4 (DLL4))
Andere Bezeichnung: sDLL4 (DLL4 Produkte)
Hintergrund: Human sDLL4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. DLL4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL4 gene in mice resulted in severe vascular defects and death before birth.
Alternative Names: sDLL-4 protein, sDLL 4 protein, sDLL 4, sDLL4, sDLL-4 protein, Delta-like protein 4, Drosophila Delta homolog 4 protein, sDLL-4
Molekulargewicht: 54 kDa
Pathways: Notch Signalweg

DLL4 Protein