Cytokeratin 18 Protein
Kurzübersicht für Cytokeratin 18 Protein (ABIN935277)
Target
Alle Cytokeratin 18 (KRT18) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
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Produktmerkmale
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Purified recombinant Human Cytokeratin 18 protein
Expression System: E.coli
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Keratin 18 (KRT18) (AA 1-430) protein (His tag)
KRT18 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Keratin 18 (KRT18) (AA 1-430) protein (GST tag)KRT18 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Protein standard in 1D and 2D SDS gel electrophoresis, Immunoassays, Immunization
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute with 175 μL distilled water (final volume 250 μL)
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Buffer
- Lyophilized from solution containing 30 mM Tris/HCI pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA, and 10 mM methylammonium chloride.
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Vorsichtsmaßnahmen
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Andere Bezeichnung
- Cytokeratin 18
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Hintergrund
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Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alternative Names: Cytokeratin 18 protein, Cytokeratin 18, Cytokeratin-18 protein, Cytokeratin-18, Keratin K18 protein, Cytokeratin 18 -
Molekulargewicht
- 45 kDa
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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