APOA1 Protein

Produktnummer ABIN935203

Recombinant APOA1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für APOA1 Protein (ABIN935203)

Target: APOA1 (Apolipoprotein A-I (APOA1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: MDEPPQSPWD RVKDLATVYV DVLKDSGRDY VSQFEGSALG KQLNLKLLDN WDSVTSTFSK LREQLGPVTQ EFWDNLEKET EGLRQEMSKD LEEVKAKVQP YLDDFQKKWQ EEMELYRQKV EPLRAELQEG ARQKLHELQE KLSPLGEEMR DRARAHVDAL RTHLAPYSDE LRQRLAARLE ALKENGGARL AEYHAKATEH LSTLSEKAKP ALEDLRQGLL PVLESFKVSF LSALEEYTKK LNTQ

Produktmerkmale: Purified recombinant Human ApoA-I protein
Expression System: E.coli

Endotoxin-Niveau: < 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 1.0 mg/mL.

Buffer: Lyophilized from 5 mM Na3PO4, pH 7.5.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: APOA1 (Apolipoprotein A-I (APOA1))

Andere Bezeichnung: ApoA-I

Hintergrund: ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis.
Alternative Names: Apolipoprotein A-I protein, ApoA I protein, ApoA1 protein, Apo AI protein

Molekulargewicht: 28.2 kDa

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism