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ApoE3 Protein

Dieses Recombinant ApoE3-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN935201

Kurzübersicht für ApoE3 Protein (ABIN935201)

Target

ApoE3 (Apolipoprotein E3 (ApoE3))

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 5
Escherichia coli (E. coli)

Reinheit

> 90 % pure
  • Sequenz

    MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH

    Produktmerkmale

    Purified recombinant Human ApoE3 protein
    Expression System: E.coli

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in 20 mM Sodium Phosphate, pH 7.8, and 0.5 mM DTT to a concentration of 1.0 mg/mL. Do not vortex. This solution can be stored at 4 °C for one week.

    Buffer

    Lyophilized from 20 mM Na3PO4, pH 7.8, with 0.5 mM DTT.

    Konservierungsmittel

    Dithiothreitol (DTT)

    Vorsichtsmaßnahmen

    This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    ApoE3 (Apolipoprotein E3 (ApoE3))

    Andere Bezeichnung

    ApoE3

    Hintergrund

    ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90 % of the population.
    Alternative Names: Apoprotein E3 protein, Apo-E3 protein, Apo E3 protein, ApoE3, ApoE 3, ApoE-3 protein, ApoE-3, ApoE 3 protein

    Molekulargewicht

    34.0 kDa

    Pathways

    Regulation of Cell Size, Lipid Metabolism
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