ApoE3 Protein

Produktnummer ABIN935201

Produktdetails

Target: ApoE3 (Apolipoprotein E3 (ApoE3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH

Produktmerkmale: Purified recombinant Human ApoE3 protein
Expression System: E.coli

Reinheit: > 90 % pure

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 20 mM Sodium Phosphate, pH 7.8, and 0.5 mM DTT to a concentration of 1.0 mg/mL. Do not vortex. This solution can be stored at 4 °C for one week.

Buffer: Lyophilized from 20 mM Na3PO4, pH 7.8, with 0.5 mM DTT.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: ApoE3 (Apolipoprotein E3 (ApoE3))

Andere Bezeichnung: ApoE3 (ApoE3 Produkte)

Hintergrund: ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90 % of the population.
Alternative Names: Apoprotein E3 protein, Apo-E3 protein, Apo E3 protein, ApoE3, ApoE 3, ApoE-3 protein, ApoE-3, ApoE 3 protein

Molekulargewicht: 34.0 kDa

Pathways: Regulation of Cell Size, Lipid Metabolism