Cytokeratin 18 Protein

Produktnummer ABIN935141

Produktdetails

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Protein-Typ: Native

Spezies: Rind (Kuh)

Quelle: Cow

Produktmerkmale: Purified native Bovine Keratin K18 Protein
Protein Source: Bovine liver

Reinheit: > 95 % pure

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 1 mg/mL

Buffer: Supplied in lyophilized form with 30 mM Tris/HCI pH 8.0, 9 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.

Antigendetails

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: Keratin K18 (KRT18 Produkte)

Hintergrund: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Description: Bovine liver.
Alternative Names: Keratin K 18, Cytokeratin 18 protein, Keratin 18 protein, Keratin K-18, Keratin K18, Keratin K-18 protein, Keratin K 18 protein

Molekulargewicht: 45 kDa

Pathways: Apoptose, Caspase Kaskade in der Apoptose