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FEN1 Protein (AA 1-380)

Recombinant FEN1-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN935077

Kurzübersicht für FEN1 Protein (AA 1-380) (ABIN935077)

Target

Alle FEN1 Proteine anzeigen
FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Protein-Typ

Recombinant

Spezies

  • 7
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  • 1
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Human

Quelle

  • 40
  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Applikation

SDS-PAGE (SDS)

Reinheit

> 90 % pure
  • Proteineigenschaft

    AA 1-380

    Sequenz

    MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK

    Produktmerkmale

    Purified recombinant Human FEN1 protein
    Expression System: E.coli
  • Möchten Sie weitere Optionen für dieses Protein ?

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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 13.711,36 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

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  • Applikationshinweise

    FEN1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT and 10 % glycerol.

    Konservierungsmittel

    Dithiothreitol (DTT)

    Vorsichtsmaßnahmen

    This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C

    Informationen zur Lagerung

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

    Andere Bezeichnung

    FEN1

    Hintergrund

    FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
    Alternative Names: Flap structure specific endonuclease 1 protein, Flap endonuclease 1 protein, Maturation factor 1 protein, MF1 protein, hFEN1 protein, RAD2 protein, FEN 1, FEN-1, Flap structure-specific endonuclease 1 DNase IV protein, FEN 1 protein, FEN-1 protein, FEN-1 protein, , FEN1

    Molekulargewicht

    42.5 kDa (380 AA)

    Pathways

    Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
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