Troponin I Protein (TNNI)

Produktnummer ABIN934438

Native Troponin I-Protein exprimiert in Schwein.

Kurzübersicht für Troponin I Protein (TNNI) (ABIN934438)

Target: Troponin I (TNNI)

Protein-Typ: Native

Spezies: Schwein

Quelle: Schwein

Reinheit: > 90 % pure

Produktdetails

Produktmerkmale: Purified native Pig Troponin I protein (Cardiac)
Protein Source: Cardiac Tissue

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25-2.0 mg/mL

Buffer: Supplied in 8 M Urea, 50 mM Tris.HCl, 5 mM beta-mercaptoethanol, 2 mM EDTA, 0.5 mM CaCl2, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -25 °C or below.

Antigendetails

Target: Troponin I (TNNI)

Andere Bezeichnung: Troponin I

Hintergrund: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Description: Cardiac Tissue.
Alternative Names: Cardiac-specific troponin I protein, Troponin I protein, cTnl protein, TnI protein

Molekulargewicht: 22-24 kDa