Troponin I Protein (TNNI)

Produktnummer ABIN934731

Produktdetails

Target: Troponin I (TNNI)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Produktmerkmale: Purified Recombinant Human Troponin I protein (Cardiac)
Expression System: E.coli

Reinheit: > 98 % pure

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Supplied in 6 M Urea, 56 M Tris, pH 8.0

Vorsichtsmaßnahmen: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -25 °C.

Referenzen

Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

Antigendetails

Target: Troponin I (TNNI)

Andere Bezeichnung: Troponin I (TNNI Produkte)

Synonyme: CG7178 Protein, DROTROPONI Protein, DmTpnI Protein, Dmel\\CG7178 Protein, HDP Protein, HL-I Protein, HL08042 Protein, HLI Protein, Tn I Protein, TnI Protein, TpnI Protein, WupA Protein, hdp Protein, hdp2 Protein, wup-A Protein, tni Protein, wings up A Protein, troponin I Protein, putative troponin I Protein, wupA Protein, tni Protein, LOC5574015 Protein, Smp_059170.1 Protein

Hintergrund: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Description: E.coli.

Molekulargewicht: 24 kDa