IL-2 Protein

Produktnummer ABIN8057021

Recombinant IL-2-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für IL-2 Protein (ABIN8057021)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Cell Culture (CC)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human Interleukin-2/IL-2 Protein (active)

Sequenz: Ala 21-Thr 153

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: ≤0.01 EU per μg by the LAL method.

Biological Activity Comment: Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2

Hintergrund: Interleukin-2,IL-2,T-Cell Growth Factor,TCGF,Aldesleukin,Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

Molekulargewicht:

Calculated MW: 15.4 kDa

Observed MW: 14-22 kDa

UniProt: P60568-1

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation