TET1 Protein (AA 1634-1986, AA 2601-2708)

Produktnummer ABIN7939796

Dieses Recombinant TET1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für TET1 Protein (AA 1634-1986, AA 2601-2708) (ABIN7939796)

Target: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Protein-Typ: Recombinant

Spezies: Drosophila melanogaster

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 1634-1986, AA 2601-2708

Verwendungszweck: Recombinant DmTet (1634-1986, 2601-2708) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant DmTet (1634-1986 and 2601-2708) protein is supplied in 25 mM Tris pH 7.4, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Andere Bezeichnung: DmTet

Hintergrund:

Protein Background: Ten Eleven Translocation (TET) family proteins are cytosine oxygenases that catalyze the conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). 5hmC can be further oxidized into 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by TET proteins. Methylation at the C5 position of cytosine is an epigenetic modification of the mammalian genome that plays an important role in transcriptional regulation. TET proteins are responsible for initiating the enzymatic deamination process leading to cytosine demethylation.

Short Description: Recombinant DmTet (1634-1986 and 2601-2708) protein was expressed in E. colicells as the Protein fragment (accession number NP_001246581.1) with an N-terminal 6xHis tag. The molecular weight of DmTet (1634-1986 and 2601-2708) is 53.68 kDa.

Aliases: Drosophila melanogaster Tet-like protein

Pathways: Stem Cell Maintenance, Warburg Effekt