STAT4 Protein
Kurzübersicht für STAT4 Protein (ABIN7939572)
Target
Alle STAT4 Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
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Verwendungszweck
- Recombinant STAT4 protein
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Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 11.737,02 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 15.754,29 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Recombinant STAT4 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handhabung
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Andere Bezeichnung
- STAT4
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Hintergrund
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Protein Background: STAT4 (Signal transducer and activator of transcription 4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane and then dimerized STAT4 translocates to the nucleus to regulate gene expression. STAT4 play an essential role in a wide variety of cells and the pathogenesis of diverse human diseases, especially many kinds of autoimmune and inflammatory diseases, via activation by different cytokines through the Janus kinase (JAK)-STAT signaling pathway.
Short Description: Recombinant STAT4 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003142.1) with an N-terminal FLAG tag. The molecular weight of the protein is 87.21 kDa.
Aliases: SLEB11, DPMC
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Pathways
- JAK-STAT Signalweg
Target
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