Glucagon Protein (GCG) (His tag)

Produktnummer ABIN7938858

Dieses Recombinant Glucagon-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für Glucagon Protein (GCG) (His tag) (ABIN7938858)

Target: Glucagon (GCG)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Aufreinigungstag / Konjugat: Dieses Glucagon Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant GLU protein

Produktmerkmale: GLU protein was expressed in E. coli (accession number NP_001028216.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 43.1 kDa.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant GLU protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: Glucagon (GCG)

Andere Bezeichnung: GLU

Hintergrund:

Protein Background: GLU (Glutamine synthetase), also called as GLU, is an enzymatic that catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Short Description: GLU protein was expressed in E. coli cells (accession number NP_001028216.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 43.1 kDa.

Aliases: Glutamine synthetase

Molekulargewicht: 43.1 kDa

NCBI Accession: NP_001028216

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling