ALKBH1 Protein
Kurzübersicht für ALKBH1 Protein (ABIN7938582)
Target
Alle ALKBH1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
-
-
Verwendungszweck
- Recombinant ALKBH1 protein
-
Produktmerkmale
- ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 11.737,02 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 15.754,29 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (His tag)
custom-made ALKBH1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (His tag)custom-made ALKBH1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (GST tag)ALKBH1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
AlkB, Alkylation Repair Homolog 1 (ALKBH1) protein (Myc-DYKDDDDK Tag)ALKBH1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Recombinant ALKBH1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.
-
Handhabung
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
Lagerung
- -80 °C
-
Informationen zur Lagerung
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
-
Andere Bezeichnung
- ALKBH1
-
Hintergrund
-
Protein Background: ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.
Short Description: Full length ALKBH1 protein (accession number NP_006011.2) was expressed in E.coli cells with an N-terminal 6xHis Tag. The molecular weight of ALKBH1 is 47.6 kDa.
Aliases: AlkB Homolog 1, Histone H2A Dioxygenase
-
Pathways
- DNA Reparatur
Target
-
