14-3-3 zeta Protein (YWHAZ)

Produktnummer ABIN7938564

Dieses Recombinant 14-3-3 zeta-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für 14-3-3 zeta Protein (YWHAZ) (ABIN7938564)

Target: 14-3-3 zeta (YWHAZ)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant YWHAZ protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant YWHAZ protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: 14-3-3 zeta (YWHAZ)

Andere Bezeichnung: YWHAZ

Hintergrund:

Protein Background: YWHAZ (14-3-3 protein zeta/delta) is a adapter protein, Implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation.

Short Description: Recombinant YWHAZ protein that includes full length of human YWHAZ protein (accession number NP_001129171.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 29.91 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

Aliases: 14-3-3 Protein Zeta/Delta, KCIP, Activation Protein, Delta Polypeptide, YWHAD, HEL4, Protein Kinase C, Inhibitor Protein 1

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location